The synthesis of amines by the homogeneous hydrogenation of secondary and primary amides

Literature Information

Publication Date 2007-07-06
DOI 10.1039/B706635J
Impact Factor 6.222
Authors

Angel A. Núñez Magro, Graham R. Eastham, David J. Cole-Hamilton



Abstract

Amides can be hydrogenated to amines using a catalyst prepared in situ from [Ru(acac)3] and 1,1,1-tris(diphenylphosphinomethyl)ethane; water is required to stabilize the catalyst and primary amines can only be formed (selectivity up to 85%) if ammonia is also present.

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

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