Catalogue of self-targeting nano-medical inventions to accelerate clinical trials
文献信息
Samar A. Alsudir
Repetitive outbreaks and prolonged epidemics represent mortal threats to global health, creating chaos in our globalized world. To date, scientists have been compelled to follow FDA guidelines for conventional clinical trials, which decelerates the release of effective therapies to battle outbreaks and safeguard global health security. Developing multi-purpose platform nanotechnologies to self-target specific organs in response to the disease microenvironment could greatly help to rapidly anticipate and efficiently manage outbreaks. Nano-interventions in the form of self-targeting nanoparticles (NPs) could accelerate the clinical translation of potential drugs to fight future outbreaks via innovating their clinical trials. This review sets the foundation of the self-targeting concept to govern the in vivo fate of NPs without the need to complicate the engineering designs with targeting ligands. The proposed catalogue of accelerated nano-innovations offers self-targeting, physiological trafficking, bio-compliance, and controllable drug release in response to associated smart linkers.
相关文献
IF 6.367
From zinco(ii) arsaketenes to silylene-stabilised zinco arsinidene complexesIF 6.222
The limits to biocatalysis: pushing the envelopeIF 6.222
An aminophosphonate ester ligand-containing platinum(ii) complex induces potent immunogenic cell death in vitro and elicits effective anti-tumour immune responses in vivoIF 6.222
Performance of electrode-supported silica membrane separators in lithium-ion batteriesIF 6.367
Boronic acid liposomes for cellular delivery and content release driven by carbohydrate binding‡IF 6.222
Chemoproteomics-based target profiling of sinomenine reveals multiple protein regulators of inflammationIF 6.222
Direct arylation polycondensation towards water/alcohol-soluble conjugated polymers as the electron transporting layers for organic solar cellsIF 6.222
Strong circularly polarized luminescence of an octahedral chromium(iii) complexIF 6.222
In situ growth of all-inorganic perovskite nanocrystals on black phosphorus nanosheetsIF 6.222
来源期刊
Biomaterials Science
Biomaterials Science is an international high impact journal exploring the science of biomaterials and their translation towards clinical use. Its scope encompasses new concepts in biomaterials design, studies into the interaction of biomaterials with the body, and the use of materials to answer fundamental biological questions. Papers do not necessarily need to report a new biomaterial but should provide novel insight into the biological applications of the biomaterial. Articles that primarily focus on demonstrating novel materials chemistry and bring a molecular picture to bear on a given material’s suitability as a biomaterial are more suited to our companion journal, Journal of Materials Chemistry B. Biomaterials Science publishes primary research and review-type articles in the following areas: molecular design of biomaterials, including translation of emerging chemistries to biomaterials science of cells and materials at the nanoscale and microscale materials as model systems for stem cell and human biology materials for tissue engineering and regenerative medicine (Nano)materials and (nano)systems for therapeutic delivery interactions at the biointerface biologically inspired and biomimetic materials, including bio-inspired self-assembly systems and cell-inspired synthetic tools next-generation biomaterials tools and methods
推荐供应商
大连普瑞特化工科技有限公司宝鸡宝冶钛镍制造有限责任公司
WS INSEBO GmbH赤峰瑞阳化工有限公司
劳工技术塔斯勒(LTT)有限公司ZIAG工厂工程有限公司广州观泓生物科技有限公司天津立悦合信科技有限公司罗姆贝格机械厂建德市永固塑料设备厂