Catalogue of self-targeting nano-medical inventions to accelerate clinical trials
文献情報
Samar A. Alsudir
Repetitive outbreaks and prolonged epidemics represent mortal threats to global health, creating chaos in our globalized world. To date, scientists have been compelled to follow FDA guidelines for conventional clinical trials, which decelerates the release of effective therapies to battle outbreaks and safeguard global health security. Developing multi-purpose platform nanotechnologies to self-target specific organs in response to the disease microenvironment could greatly help to rapidly anticipate and efficiently manage outbreaks. Nano-interventions in the form of self-targeting nanoparticles (NPs) could accelerate the clinical translation of potential drugs to fight future outbreaks via innovating their clinical trials. This review sets the foundation of the self-targeting concept to govern the in vivo fate of NPs without the need to complicate the engineering designs with targeting ligands. The proposed catalogue of accelerated nano-innovations offers self-targeting, physiological trafficking, bio-compliance, and controllable drug release in response to associated smart linkers.
関連文献
IF 6.222
Permselective ion electrosorption of subnanometer pores at high molar strength enables capacitive deionization of saline waterIF 6.367
Effective utilisation of waste cooking oil in a single-cylinder diesel engine using alumina nanoparticlesIF 6.367
The dilemma between acid and base catalysis in the synthesis of benzimidazole from o-phenylenediamine and carbon dioxide‡IF 6.222
An aminophosphonate ester ligand-containing platinum(ii) complex induces potent immunogenic cell death in vitro and elicits effective anti-tumour immune responses in vivoIF 6.222
Mechanically stable and economically viable polyvinyl alcohol-based membranes with sulfonated carbon nanotubes for proton exchange membrane fuel cellsIF 6.367
Catalytic depolymerization of alkali lignin in ionic liquids on Pt-supported La2O3–SO42−/ZrO2 catalystsIF 6.367
High-performance tungsten carbide electrocatalysts for the hydrogen evolution reactionIF 6.367
Milk exosomes with enhanced mucus penetrability for oral delivery of siRNAIF 6.843
Photoactivatable fluorophores for durable labelling of individual cellsIF 6.222
掲載誌
Biomaterials Science
Biomaterials Science is an international high impact journal exploring the science of biomaterials and their translation towards clinical use. Its scope encompasses new concepts in biomaterials design, studies into the interaction of biomaterials with the body, and the use of materials to answer fundamental biological questions. Papers do not necessarily need to report a new biomaterial but should provide novel insight into the biological applications of the biomaterial. Articles that primarily focus on demonstrating novel materials chemistry and bring a molecular picture to bear on a given material’s suitability as a biomaterial are more suited to our companion journal, Journal of Materials Chemistry B. Biomaterials Science publishes primary research and review-type articles in the following areas: molecular design of biomaterials, including translation of emerging chemistries to biomaterials science of cells and materials at the nanoscale and microscale materials as model systems for stem cell and human biology materials for tissue engineering and regenerative medicine (Nano)materials and (nano)systems for therapeutic delivery interactions at the biointerface biologically inspired and biomimetic materials, including bio-inspired self-assembly systems and cell-inspired synthetic tools next-generation biomaterials tools and methods
![1337532-29-2 - 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone](/structs/133/1337532-29-2-edb6.webp "1337532-29-2 - 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone")
おすすめサプライヤー
Variati & Co.S.p.a.
山東和輝国際貿易有限公司
ApiniLabs株式会社山東格隆立博株式有限公司。山东亿淳化学有限公司上海徳祥医药技術有限公司
Verrerie Soufflée Mécanique (VSM) S.A.
エンテグリス株式会社上海菱晓貿易有限公司
M—Tech Fr ö schl 、 Maschinen—und Anlagenbau GmbH