Synthesis and in vitro assessment of a bifunctional closomer probe for fluorine (19F) magnetic resonance and optical bimodal cellular imaging

文献信息

发布日期 2014-04-15
DOI 10.1039/C4CC02126F
影响因子 6.222
作者

Lalit N. Goswami, Aslam A. Khan, Satish S. Jalisatgi, M. Frederick Hawthorne



摘要

The design, synthesis and in vitro assessment of a bifunctional imaging probe for dual fluorine (19F) magnetic resonance spectroscopy (19F-MRS) and fluorescence detection is reported. Eleven copies of 3,5-bis(trifluoromethyl)phenyl and a single copy of a sulforhodamine-B were covalently attached to a closo-B122−-core via suitable linkers. The 19F-MRS and fluorescence imaging shows that, this novel bimodal imaging probe was readily taken up by the cells in vitro after co-incubation.

来源期刊

Chemical Communications

Chemical Communications
CiteScore: 8.6
自引率: 4.7%
年发文量: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

推荐供应商

中国西安博康兴业食用化工有限公司
德国Systec GmbH&Co.KG
中国涟水县依顺环保有限公司
中国山东合晖国际贸易有限公司
德国Ludwig Melosch Vertriebs-GmbH & Co.
中国江苏金沃新材料有限公司
中国常州凯康生物科技有限公司
中国昂得生化科技(上海)有限公司
德国AstroNova GmbH
中国陕西晨曦之光化学科技有限公司
免责声明
本页面提供的学术期刊信息仅供参考和研究使用。我们与任何期刊出版商均无关联,也不处理投稿事宜。如有投稿相关咨询,请直接联系相关期刊出版商。
如发现页面信息有误,请发送邮件至 [email protected] 联系我们。我们将及时核实并处理您的问题。