Amphiphilic nanogel of enzymatically synthesized glycogen as an artificial molecular chaperone for effective protein refolding

文献信息

发布日期 2013-10-28
DOI 10.1039/C3RA44572K
影响因子 3.361
作者

Shigeo Takeda, Haruko Takahashi, Yoshihiro Sasaki



摘要

Enzymatically synthesized glycogen (ESG) bearing hydrophobic groups were prepared to construct a new artificial molecular chaperone system. The radius of the amphiphilic ESG nanogel was approximately 15 nm. The nanogels prevented irreversible aggregation of carbonic anhydrase. Cyclodextrin induced the release of carbonic anhydrase in its active form via a one-step mechanism without dissociation of the nanogels.

来源期刊

RSC Advances

RSC Advances
CiteScore: 7.5
自引率: 2.6%
年发文量: 3122

Chemistry fascinates us. This discipline is integral to life and impacts so many aspects of our world. The scope for RSC Advances is wide-ranging because we want to capture any research that can offer crucial insights and advance chemistry. RSC Advances papers should provide an insight that advances the chemistry field. Papers that contain little or no chemistry and are not considered to be of interest or relevance to the chemistry community are not within the scope of the journal. The criteria for publication are that the work must be high quality, well conducted and advance the development of the field. Articles submitted to the journal are evaluated by our international team of associate editors and reviewers for the overall quality and accuracy of the science presented. Download our full list of subject categories to see the range of topics we publish in RSC Advances. Please ensure you have considered the following points before submitting your manuscript. Does the work present an advance over the existing literature? Please supply a covering letter with your submission to demonstrate how the work is advancing the field over the existing literature Have you provided sufficient evidence/data to support your conclusions? Have you provided adequate characterisation data for your materials/compounds? (Please check the supporting information section to ensure that the necessary requirements have been met and copies of relevant spectra have been provided where necessary) Are the results discussed in the context of the literature? Are the references relevant and do they appropriately reflect the existing literature?

推荐供应商

中国青岛玉洲化工有限公司(山东莱西
中国溧阳市长青化工有限公司
中国山东合展化工有限公司
印度生物链公司
中国杭州海达医药化工有限公司
阿根廷赫尔姆阿根廷SRL
德国FWA Friedrich Werntges Apparatebau GmbH
德国格斯特拉 AG
美国Sila纳米技术股份有限公司。
中国石家庄超微新材料科技有限公司
免责声明
本页面提供的学术期刊信息仅供参考和研究使用。我们与任何期刊出版商均无关联,也不处理投稿事宜。如有投稿相关咨询,请直接联系相关期刊出版商。
如发现页面信息有误,请发送邮件至 [email protected] 联系我们。我们将及时核实并处理您的问题。