Janus functional electrospun polyurethane fibrous membranes for periodontal tissue regeneration
Literature Information
Jingjing Lin, Yushui He, Yuanyuan He, Yuan Feng, Xiao Wang, Lei Yuan, Jie Chen, Feng Luo, Zhen Li, Jiehua Li, Hong Tan
The guided tissue regeneration (GTR) technique with GTR membranes is an efficient method for repairing periodontal defects. Conventional periodontal membranes act as physical barriers that resist the growth of fibroblasts, epithelial cells, and connective tissue. However, they cannot facilitate the regeneration of periodontal tissue. To address this issue, the exploitation of novel GTR membranes with bioactive functions based on therapeutic requirements is critical. Herein, we exploited a biodegradable bilayer polyurethane fibrous membrane by uniaxial electrostatic spinning to construct two sides with Janus properties by integrating the bioactive molecule dopamine (DA) and antimicrobial Gemini quaternary ammonium salt (QAS). The DA-containing side, located inside the injury, can effectively promote cell adhesion and mesenchymal stem cell growth as well as support mineralization and antioxidant properties, which are beneficial for bone regeneration. The QAS-containing side, located on the outer surface of the injury, endows antibacterial properties and limits fibroblast adhesion and growth on its surface owing to its strong hydrophilicity. An in vivo study demonstrates that the Janus polyurethane fibrous membrane can significantly promote the regeneration of periodontal defects in rats. Owing to its superior mechanical properties and biocompatibility, this polyurethane fibrous membrane has potential applications in the field of periodontal regeneration.
Related Literature
IF 6.222
Front coverIF 6.843
Palladium-catalyzed silaborative carbocyclizations of 1,6-diynesIF 6.222
A hollow neuronal carbon skeleton with ultrahigh pyridinic N content as a self-supporting potassium-ion battery anodeIF 6.367
Developing a novel high performance NaNbO3-based lead-free dielectric capacitor for energy storage applicationsIF 6.367
High-performance tungsten carbide electrocatalysts for the hydrogen evolution reactionIF 6.367
Metal–organic frameworks: preparation and applications in highly efficient heterogeneous photocatalysisIF 6.367
Non-aqueous neptunium and plutonium redox behaviour in THF – access to a rare Np(iii) synthetic precursorIF 6.222
A robust multifunctional ligand-controlled palladium-catalyzed carbonylation reaction in waterIF 6.222
Vapor-fed photoelectrolysis of water at 0.3 V using gas-diffusion photoanodes of SrTiO3 layersIF 6.367
Source Journal
Journal of Materials Chemistry B
Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. The journals have a strong history of publishing quality reports of interest to interdisciplinary communities and providing an efficient and rigorous service through peer review and publication. The journals are led by an international team of Editors-in-Chief and Associate Editors who are all active researchers in their fields. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C. More than one Journal of Materials Chemistry journal may be suitable for certain fields and researchers are encouraged to submit their paper to the journal that they feel best fits for their particular article. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive. Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices image block All articles published in Journal of Materials Chemistry B from 2019 onwards will be indexed in MEDLINE®. Articles that primarily focus on providing insight into the underlying science and performance of biomaterials within a biological environment are more suited to our companion journal, Biomaterials Science.
Recommended Compounds
Recommended Suppliers
INTAS Science Imaging Instruments GmbH
Química Vita, S.A. de C.V.
Zhejiang Longyuan Filter Press Co., LtdSystec GmbH & Co. KGhps Labor- und Bürositzmöbel OHG
Elemental Scientific Inc.KABELSCHLEPP GmbHIndustriepark PremnitzTaizhou Jia Yin Chemical Co., Ltd.Shandong Mezhen Biotechnology Co., Ltd.