Sensitive and specific detection of tumour cells based on a multivalent DNA nanocreeper and a multiplexed fluorescence supersandwich

Literature Information

Publication Date 2020-02-21
DOI 10.1039/C9CC08618H
Impact Factor 6.222
Authors

Lei Luo, Wenshan Li, Dongliu Xiang, Yanyun Ma, Yuan Zhou, Yaqing Xu, Nandi Chen, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang, Kemin Wang



Abstract

A self-assembled DNA nanostructure based on a DNA nanocreeper and multiplexed fluorescence supersandwich was designed for the sensitive and specific detection of tumour cells. This nanostructure could improve the binding affinity of current aptamers and trigger signal amplification, which provide potential for the discrimination of low abundant target cells in liquid biopsy.

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Suppliers

ChinaLiaoning Huaxing Corporation Limited
United StatesZapata Computing, Inc.
GermanyBertrandt Services GmbH
ChinaZoucheng Tianxing Chemical Co., Ltd.
GermanyInterstuhl Büromöbel GmbH & Co. KG
GermanyFrank Gutjahr Chromatographie
ChinaShenzhen Youshou Biology Technology Co., Ltd. Huangshi Branch
ChinaGuangzhou Xiangmei Chemical Technology Co., Ltd.
ChinaNanjing Yanqiao Technology Co., Ltd.
GermanyEdelstahlservice Sulz GmbH
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at [email protected]. We will promptly review and address your concerns.