Transition-metal-free insertion reactions of alkynes into the C–N σ-bonds of imides: synthesis of substituted enamides or chromones
Literature Information
Zhong Zheng, Ye Wang, Murong Xu, Lingkai Kong, Mengdan Wang, Yanzhong Li
A transition-metal-free tandem process for the synthesis of substituted enamides and chromones is presented. The insertion of isolated alkynes into the C–N σ-bonds of imides is involved in this tandem process. In the case of alkynones bearing an ortho-bromo-substituted aryl ring, chromones were selectively formed via the O-cyclization pathway. A variety of substituted enamides and chromones were prepared in good to high yields.
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Chemical Communications

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