Transition-metal-free insertion reactions of alkynes into the C–N σ-bonds of imides: synthesis of substituted enamides or chromones

Literature Information

Publication Date 2018-05-23
DOI 10.1039/C8CC03059F
Impact Factor 6.222
Authors

Zhong Zheng, Ye Wang, Murong Xu, Lingkai Kong, Mengdan Wang, Yanzhong Li



Abstract

A transition-metal-free tandem process for the synthesis of substituted enamides and chromones is presented. The insertion of isolated alkynes into the C–N σ-bonds of imides is involved in this tandem process. In the case of alkynones bearing an ortho-bromo-substituted aryl ring, chromones were selectively formed via the O-cyclization pathway. A variety of substituted enamides and chromones were prepared in good to high yields.

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Suppliers

GermanySchwedes + Schulze Schüttguttechnik GmbH
ChinaLianwater County Yishun Environmental Protection Co., Ltd.
ChinaTaixing Chemical Co., Ltd.
ChinaShandong Academy of Pharmaceutical Sciences Pilot Plant
ChinaNingbo Zhenlei Chemical Co., Ltd.
ChinaWuxi Huier Environmental Testing Equipment Factory
AustriaLOBA Feinchemie AG
ChinaGuangdong Huilian_DA Chemical Co., Ltd.
GermanyHST Maschinbau GmbH
ChinaShandong Xishangxi New Materials Shareholding Co., Ltd. (API)
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at [email protected]. We will promptly review and address your concerns.