Novel triazole-based fluorescent probes for Pd2+ in aqueous solutions: design, theoretical calculations and imaging
Literature Information
Ji-Ting Hou, Kun Li, Kang-Kang Yu, Mei-Zhen Ao, Xin Wang, Xiao-Qi Yu
The first triazole-containing fluorescent probe with excellent water-solubility for Pd2+ was presented. The results indicated that an amide–triazole–amide binding sequence was responsible for the unique affinity of PS-1 toward Pd2+. Among the tested metal ions, only Pd2+ could selectively quench the fluorescence of PS-1 under physiological conditions, while other common interference ions like Pt2+ and Ru3+ caused little changes. The successful fluorescence imaging of Pd2+ in HeLa cells implied the potential applications of PS-1 in biological Pd2+-analysis.
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