Electroanalytical methodologies for the detection of S-nitrosothiols in biological fluids

Literature Information

Publication Date 2013-07-08
DOI 10.1039/C3AN00488K
Impact Factor 4.616
Authors



Abstract

The interest in the detection and quantification of S-nitrosothiols or thionitrites RSNOs in biological media and their use as pharmaceutical agents is mainly related to the discovery of nitric oxide as an endothelium relaxing factor, and analytical methodologies that are able to detect these moieties in real time, in situ and ideally with high sensitivity and selectivity could help in a better understanding of their biological pathways. In this review, we discuss the performances of the electroanalytical strategies developed for the sensing of low molecular weight RSNOs in biological fluids.

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Analyst

Analyst
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Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

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