EGFR/ErbB-2/ErbB-4 Inhibitor II(CAS番号:944341-54-2)

基本情報

EGFR/ErbB-2/ErbB-4 Inhibitor II

CAS番号

944341-54-2

分子式

C24H28Cl2N6O3

分子量

482.97 g/mol

Quick Actions

基本的な物理特性

SMILES

C1COCCN1CCON=CC2=C(N=CN=C2NC3=CC(=C(C=C3)OCC4=CC=CC=C4)Cl)N.Cl

InChI

InChI=1S/C24H27ClN6O3/c25-21-14-19(6-7-22(21)33-16-18-4-2-1-3-5-18)30-24-20(23(26)27-17-28-24)15-29-34-13-10-31-8-11-32-12-9-31/h1-7,14-15,17H,8-13,16H2,(H3,26,27,28,30)/b29-15+

InChIKey

OZWCXTYQZRVEFW-WKULSOCRSA-N

LogP

3.717500000000002

トポロジカル極性表面積

107.12 Ų

水素結合ドナー/アクセプター

3 / 9

複雑度

605

分類と用途

安全情報

安全情報を表示

同義語と参考文献

英語

  • 4-N-(3-chloro-4-phenylmethoxyphenyl)-5-(2-morpholin-4-ylethoxyiminomethyl)pyrimidine-4,6-diamine,hydrochloride
  • 5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehydeN-(2-morpholin-4-ylethyl)oximehydrochloride
  • JNJ 28871063 HYDROCHLORIDE
  • EGFR/ErbB-2/ErbB-4 Inhibitor II
  • 4-N-(3-chloro-4-phenylmethoxyphenyl)-5-[(E)-2-morpholin-4-ylethoxyiminomethyl]pyrimidine-4,6-diamine;hydrochloride
  • 4-N-(3-chloro-4-phenylmethoxyphenyl)-5-(2-morpholin-4-ylethoxyiminomethyl)pyrimidine-4,6-diamine;hydrochloride
  • N~4~-[4-(Benzyloxy)-3-chlorophenyl]-5-({[2-(morpholin-4-yl)ethoxy]imino}methyl)pyrimidine-4,6-diamine--hydrogen chloride (1/1)
  • DTXSID70849569
  • 944341-54-2

MDL_Number

MFCD12828762

CAS番号

944341-54-2

サプライヤー情報

サプライヤー名 会員レベル 認証状況 主要カテゴリー 最小注文数量 アクション
中国中国 - Shanghai Hansi Chemical Co., Ltd.
中国中国 - Shanghai Jixiang Biotechnology Co., Ltd.
中国中国 - Shanghai Aladdin Bio-Technologies Co., Ltd.
中国中国 - Hefei Novartis Biotechnology Co., Ltd.
中国中国 - Nantong Yixun Chemical Industry Co., Ltd.
中国中国 - Shandong Baiqi Biopharmaceutical Biomedical Co., Ltd.
オーストリアオーストリア - LOBA Feinchemie AG
インドインド - Nitika Chemical

関連論文

Carbon-based photocatalysts for enhanced photocatalytic reduction of CO2 to solar fuels

Mufeedah Muringa Kandy

2019-11-06 Review Article

DOI: 10.1039/C9SE00827F

Back cover

2021-06-15 Cover

DOI: 10.1039/D1CC90215F

Non-aqueous neptunium and plutonium redox behaviour in THF – access to a rare Np(iii) synthetic precursor

Nickolas H. Anderson, Suzanne C. Bart, Andrew J. Gaunt, Brian L. Scott

2018-05-08 Communication

DOI: 10.1039/C8CC02611D

Contents list

Front/Back Matter

DOI: 10.1039/D0CC90139C

Ether-functionalization of monoethanolamine (MEA) for reversible CO2 capture under solvent-free conditions with high-capacity and low-viscosity

An-Hua Liu, Jie-Jie Li, Bai-Hao Ren, Xin-Ru Sha, He Jiang, Xiao-Bing Lu

2019-12-04 Paper

DOI: 10.1039/C9SE00756C

Coexisting order and disorder within a common 40-residue amyloid-β fibril structure in Alzheimer's disease brain tissue

Ujjayini Ghosh, Wai-Ming Yau, Robert Tycko

2018-04-24 Communication

DOI: 10.1039/C8CC01967C

Selective production of monocyclic aromatic hydrocarbons from ex situ catalytic fast pyrolysis of pine over the HZSM-5 catalyst with calcium formate as a hydrogen source

Kai Li, Ze-xiang Wang, Guan Zhang, Min-shu Cui, Qiang Lu, Yong-ping Yang

2019-10-28 Paper

DOI: 10.1039/C9SE00605B

Synthesis and optical and electronic properties of one-dimensional sulfoxonium-based hybrid metal halide (CH3)3SOPbI3

Shiqiang Bai, Xizu Wang, Si Yin Tee, Siew Lay Lim, Lin Ke, Surani B. Dolmanan, Coryl Jing Jun Lee, Poh Chong Lim, Xiang Yao, Jishan Wu

2021-05-10 Communication

DOI: 10.1039/D1CC01386F

Boronic acid liposomes for cellular delivery and content release driven by carbohydrate binding‡

Xiaoyu Zhang, Daiane S. Alves, Jinchao Lou, Shelby D. Hill, Francisco N. Barrera, Michael D. Best

2018-05-21 Communication

DOI: 10.1039/C8CC00820E