(4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid | CAS No. 105464-42-4

(4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid

Basic Information

CAS Number

105464-42-4

Molecular Formula

C10H19NO5

Molecular Weight

233.26 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)N[C@H](CO)CCC(=O)O

InChI

InChI=1S/C10H19NO5/c1-10(2,3)16-9(15)11-7(6-12)4-5-8(13)14/h7,12H,4-6H2,1-3H3,(H,11,15)(H,13,14)/t7-/m0/s1

InChIKey

DCYLAKLDZHSCJV-ZETCQYMHSA-N

LogP

0.7368000000000001

Topological Polar Surface Area

95.86 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Synonyms & References

English

  • (S)-4-((tert-Butoxycarbonyl)amino)-5-hydroxypentanoic acid
  • (S)-4-Boc-5-hydroxypentanac acid dicyclohexylamine
  • (S)-4-Boc-5-hydroxypentanoic acid.DCHA
  • (4S)-4-{(tert-butoxy)carbonylamino}-5-hydroxypentanoic acid

MDL Number

MFCD00270263

FAQ

What are the physical and chemical properties of (4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid (CAS: 105464-42-4)?

The compound has a crystalline form and a molecular weight of approximately 212.27 g/mol. It is slightly soluble in water and more soluble in organic solvents. It is reactive under acidic or basic conditions, making it useful in peptide synthesis and as an intermediate in the pharmaceutical industry.

How is (4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid (CAS: 105464-42-4) typically synthesized?

(4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid is usually synthesized via a multi-step process involving protected amino acid synthesis. Commonly, the protected amino acid is made through the reaction of 5-hydroxypentanoic acid with tert-butoxycarbonyl chloride, followed by purification steps. This compound is often used in the synthesis of peptides and proteins.

What industries use (4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid (CAS: 105464-42-4)?

(4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid is primarily used in the pharmaceutical industry for the synthesis of peptides and proteins. It is also relevant in the polymer industry for the development of functional polymers and in the production of advanced materials used in sensors and semiconductors.

What precautions should be taken when handling (4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid (CAS: 105464-42-4)?

When handling (4S)-4-{[(tert-butoxy)carbonyl]amino}-5-hydroxypentanoic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and goggles. The substance should be managed under a fume hood to minimize exposure. In case of a spill, avoid direct contact and clean up using appropriate chemicals. Always consult the Safety Data Sheet (SDS) for detailed safety information and procedures.

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