4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylene bis(2,2-dimethylpropanoate) hydrochloride (1:1)（CAS号：64019-93-8）

盐酸地匹福林

基本信息

4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylene bis(2,2-dimethylpropanoate) hydrochloride (1:1)

CAS号

64019-93-8

分子式

C19H30ClNO5

分子量

387.90 g/mol

Quick Actions

基本物理性质

熔点

158-159°

沸点

473.7 °C at 760 mmHg

闪点

240.3 °C

SMILES

CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C.Cl

InChI

InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H

InChIKey

VKFAUCPBMAGVRG-UHFFFAOYSA-N

LogP

3.2642000000000024

pKa

8.40(at 25℃)

拓扑极性表面积

84.86 Å²

氢键供体/受体

2 / 6

复杂度

463

分类与用途

化学分类

医药产品原料药与中间体中间体

用途

降眼压药，用于治疗青光眼。

安全信息

同义词与参考文献

英文

UNII-5QTH9UHV0K
Dipivalyl epinephrine hydrochloride
2-[(2,2-dimethylpropanoyl)oxy]-4-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate hydrochloride
Dipivefrin hydrochloride [JAN]
HY-B1323
Alcon
EX-A8161A
EINECS 264-609-5
SCHEMBL41350
Dipivefrine (hydrochloride)
HMS1569P06
DIPIVEFRINE HYDROCHLORIDE [EP MONOGRAPH]
Dipivefrin hydrochloride (USP:JAN)
2-(3,4-bis((2,2-dimethylpropanoyl)oxy)phenyl)-2-hydroxy-N-methylethanaminium chloride
4-(1-hydroxy-2-(methylamino)ethyl)benzene-1,2-diyl bis(2,2-dimethylpropanoate) hydrochloride
Tox21_110675
CS-0013083
Dipivefrine hydrochloride
VKFAUCPBMAGVRG-UHFFFAOYSA-N
AKPro
5QTH9UHV0K
PROPANOIC ACID, 2,2-DIMETHYL-, 4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-1,2-PHENYLENE ESTER, (+/-)-, HYDROCHLORIDE
DIPIVEFRIN HYDROCHLORIDE [ORANGE BOOK]
(1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochloride
SMR001233266
NCGC00016906-01
4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate) hydrochloride
Dipivefrin hydrochloride
SR-01000838856
CHEBI:4647
64019-93-8
DTXSID2045494
Dipivefrin HCL
1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol hydrochloride
(+/-)-3,4-DIHYDROXY-.ALPHA.-((METHYLAMINO)METHYL)BENZYL ALCOHOL 3,4-DIPIVALATE HYDROCHLORIDE
Propanoic acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ester, hydrochloride, (+-)-
BCP13649
DIPIVEFRIN HYDROCHLORIDE [VANDF]
CAS-64019-93-8
DIPIVEFRINE HYDROCHLORIDE [JAN]
DIPIVALYLEPINEPHRINE HYDROCHLORIDE
D01017
(+/-)-3,4-DIHYDROXY-alpha-((METHYLAMINO)METHYL)BENZYL ALCOHOL 3,4-DIPIVALATE HYDROCHLORIDE
Dipivefrin hydrochloride (JAN/USP)
64019-93-8 (HCl)
Q27106427
(+-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol 3,4-dipivalate hydrochloride
Dipivefrine for system suitability
DIPIVEFRIN HYDROCHLORIDE [MI]
(RS)-4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-O-PHENYLENE DIPIVALATE HYDROCHLORIDE
DIPIVEFRIN HYDROCHLORIDE (USP MONOGRAPH)
DIPIVEFRINE HYDROCHLORIDE [WHO-DD]
Propine (TN)
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate;hydrochloride
CCG-220632
DTXCID0025494
Propanoic Acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene Ester, Hydrochloride,(+-)-
2-{3,4-bis[(2,2-dimethylpropanoyl)oxy]phenyl}-2-hydroxy-N-methylethanaminium chloride
Dipivefrin (hydrochloride)
dipivefrine HCl
MLS002153922
DIPIVEFRIN HYDROCHLORIDE [USP MONOGRAPH]
SR-01000838856-2
DIPIVEFRINE HYDROCHLORIDE [MART.]
AKOS037515482
MS-26426
Dipivefrin hydrochloride [USP:JAN]
CHEMBL1200833
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate,hydrochloride
Dipivefrine Hydrochloride
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochloride
[2-(2,2-Dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate hydrochloride
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene bis(2,2-dimethylpropanoate)
hydrochloride (1:1)

中文

盐酸地匹福林
4-(1-羟基-2-(甲基氨基)乙基)-1,2-苯二醇二特戊酸酯盐酸盐
盐酸地匹福林 EP标准品
盐酸地匹福林 USP标准品
盐酸地匹福林标准品

MDL_Number

MFCD01697462

CAS号

64019-93-8

供应商信息

供应商名称	会员等级	认证状态	主要类别	最小订购量	操作
中国 - 北京索莱宝科技有限公司
中国 - 湖北清北云研医药科技有限责任公司
中国 - 上海捷世凯生物科技有限公司
中国 - 上海绩祥生物科技有限公司
中国 - 湖北实兴化工有限公司
中国 - 上海阿拉丁生化科技股份有限公司
德国 - Supratec - Gesellschaft für Umwelt- und Verfaðstechnik mbH
中国 - 天津科跃化工技术有限公司