N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine（CAS号：2030-63-9）

氯苯吩嗪

基本信息

N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine

CAS号

2030-63-9

分子式

C27H22Cl2N4

分子量

473.41 g/mol

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基本物理性质

熔点

210-213°C

沸点

616.26°C (rough estimate)

闪点

296.7°C

折射率

1.6300 (estimate)

SMILES

CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl

InChI

InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3

InChIKey

WDQPAMHFFCXSNU-UHFFFAOYSA-N

LogP

7.489800000000005

pKa

8.37; also reported as 8.51(at 25℃)

拓扑极性表面积

42.21 Å²

氢键供体/受体

1 / 4

复杂度

829

分类与用途

化学分类

医药产品原料药与中间体中间体

安全信息

查看安全信息

危险说明

H315; H319; H335

毒性

LD50 orally in mice, rats, and guinea pigs: >4 g/kg (Stenger)

同义词与参考文献

英文

Phenazine, 3-(p-chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-
B663
SR-05000001807-1
2-Phenazinamine,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
N,5-Bis(4-chlorophenyl)-3-([1-methylethyl]imino)-3,5-dihydro-2-phenazinamine #
N,5-bis(4-chlorophenyl)-3-propan-2-ylimino-phenazin-2-amine
DTXSID7022839
GTPL9184
SCHEMBL26757
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
HY-B1046
C2866
NCGC00016600-02
CLOFAZIMINE [ORANGE BOOK]
B 663 (VAN)
HMS3370N05
AMY22515
HMS3713K13
Lamprene (TN)
CLOFAZIMINE [USAN]
J-013203
G-30320
AKOS026749881
BRD-K56614220-001-10-9
B. 663
NC00409
Pharmakon1600-01505974
SMR000058704
Phenazine, 2,10-dihydro-3-(p-chloroanilino)-10-(p-chlorophenyl)-2-(isopropylimino)-
Chlofazimine
C06915
cid_2794
(3E)-N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine
DB00845
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin [German]
NS00011720
N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine
3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin
2030-63-9
CLOFAZIMINE [VANDF]
CHEMBL1083384
CLOFAZIMINE [USP-RS]
Tox21_110516
HMS3652A16
HMS2052B05
(3Z)-N,5-bis(4-chlorophenyl)-3-[(1-methylethyl)imino]-3,5-dihydrophenazin-2-amine
Prestwick0_000376
SCHEMBL26758
Clofazimine, European Pharmacopoeia (EP) Reference Standard
2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-
NSC-141046
MLS006010789
B 663, pharmaceutical
Clofazimine for system suitability, European Pharmacopoeia (EP) Reference Standard
HMS2096K13
CLOFAZIMINE [EP MONOGRAPH]
HMS3394B05
EINECS 217-980-2
KS-1412
CLOFAZIMINE [INN]
MLS000028617
MMV687800
NCGC00016600-07
NCGC00016600-09
SR-05000001807-2
MLS001424318
Clofazimine [USAN:USP:INN:BAN]
SR-01000000259-6
N,5-bis(4-chlorophenyl)-3-[(propan-2-yl)imino]-3,5-dihydrophenazin-2-amine
3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine
CLOFAZIMINE [USP IMPURITY]
2-Phenazinamine,5-dihydro-N,5-bis(4-chlorophenyl)-3-[(1-methylethyl)imino]-
Prestwick2_000376
CCG-269477
BCP07792
CLOFAZIMINE [JAN]
NSC-759283
SMR004701474
Clofazimine 100 microg/mL in Acetonitrile
Phenazine,10-dihydro-2-(isopropylimino)-
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine
2458811-14-6
B-663
N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine
BIDD:PXR0147
Phenazine,10-dihydro-3-(p-chloroanilino)-10-(p-chlorophenyl)-2-(isopropylimino)-
Clofaziminum
(4-Chloro-phenyl)-[5-(4-chloro-phenyl)-3-isopropylimino-3,5-dihydro-phenazin-2-yl]-amine
Prestwick3_000376
2-Phenazinamine, 3,5-dihydro-N,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino)-
3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine
NCGC00179529-01
D959AE5USF
Clofazimina
CPD000058704
UNII-D959AE5USF
SPBio_002452
BSPBio_000531
N,5-bis(4-chlorophenyl)-3-propan-2-ylimino-2-phenazinamine
NCGC00016600-08
Q418611
G 30320
KUC109573N
SR-05000001807
HMS2093J10
KSC-27-052A
2-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
COLFAZIMINE [VANDF]
FT-0657414
NCGC00016600-04
D00278
BDBM50378783
NSC759283
Clofazimina [INN-Spanish]
(3E)-N,5-bis(4-chlorophenyl)-3-isopropylimino-phenazin-2-amine
s4107
(E)-N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
B 663
Prestwick_685
EN300-267815
AKOS015896438
Lamprene
SW196840-4
CLOFAZIMINE [WHO-IP]
BPBio1_000585
BDBM50318909
4-25-00-03033 (Beilstein Handbook Reference)
EN300-21680301
SR-01000000259
CAS-2030-63-9
CLOFAZIMINE [MI]
Clofazimine, United States Pharmacopeia (USP) Reference Standard
SBI-0206865.P001
Lampren
Riminophenazine
HMS1569K13
CLOFAZIMINE [WHO-DD]
WDQPAMHFFCXSNU-KRUMMXJUSA-N
SMP2_000339
N,5-bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine
Prestwick1_000376
CCG-101159
NSC 141046
CLOFAZIMINUM [WHO-IP LATIN]
Clofaziminum [INN-Latin]
Clofazimine (JAN/USP/INN)
2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
CS-4567
CLOFAZIMINE [USP MONOGRAPH]
DTXCID302839
A814428
clofazimine
HMS2231B04
Z2037279473
2-p-Chloranilino-5-p-chlorphenyl-3,5-dihydro-3-isopropylimino-phenazin
Colfazimine
SCHEMBL5663361
NSC141046
B 663 (Pharmaceutical)
NCGC00016600-03
NCGC00016600-01
MFCD00056793
BRN 0060420
N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropyliaino)phenazin-2-amine
CHEMBL1292
CHEBI:3749
CLOFAZIMINE [MART.]
NCGC00016600-05
Clofazimine
Clofazimine-d7
2-(4-Chlor-anilino)-5-(4-chlor-phenyl)-3-isopropylamino-phenazinium-betain
2-(4-chloro-anilino)-5-(4-chloro-phenyl)-3-isopropylamino-phenazinium-betaine
Clo
Clofazimine (N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine

中文

氯苯吩嗪
N,5-二(4-氯苯基)-3,5-二氢-3-(异丙亚氨基)吩嗪-2-胺
氯法齐明
(3-羧丙基)三甲基氯化铵
Clofazimine 氯法齐明
氯苯吩嗪 USP标准品
氯苯吩嗪标准品
氯法齐明 EP标准品
氯法齐明-D7
氯法齐明标准品
氯法齐明系统适用性 EP标准品
氯法齐明杂质
2-对氯苯胺基-5-对氯苯基-3,5-二氢-3-异丙亚氨基吩嗪
N,5-二(4-氯苯基)-3,5-二氢-3-(异丙基亚胺)吩嗪-2-胺
螺旋霉素

MDL_Number

MFCD00056793

CAS号

2030-63-9

Customs_Code

35040000

Merck_Index

2373

供应商信息

供应商名称	会员等级	认证状态	主要类别	最小订购量	操作
中国 - 北京索莱宝科技有限公司
中国 - 上海惠诚生物科技有限公司
中国 - 上海博飞美科化学科技有限公司
德国 - Sohena GmbH
中国 - 陕西信瑞生物科技有限公司
中国 - 天津旅畅科技发展有限公司
英国 - IMTEX控制有限公司
法国 - Cristal France SAS