Combined application of organozinc chemistry and one-pot hydroboration–Suzuki coupling to the synthesis of amino acids
Literature Information
Arantxa Rodríguez, David D. Miller, Richard F. W. Jackson
Hydroboration using 9-BBN-H of the protected enantiomerically pure but-3-enylglycine derivative 11, prepared by copper-catalysed allylation of the serine-derived organozinc reagent 1, followed by Suzuki coupling of the derived borane with a variety of aromatic halides, 2-bromopyridine and 2-bromopropene gives the protected amino acids 14a–l and 15. This method augments our previous methods for the synthesis of phenylalanine homologues.
Related Literature
Photoelectron spectroscopy of lithium and gold alloyed boron oxide clusters: charge transfer complexes, covalent gold, hyperhalogen, and dual three-center four-electron hyperbonds
Wen-Juan Tian, Hong-Guang Xu, Qiang Chen, Hua-Jin Zhai, Si-Dian Li
DOI: 10.1039/C3CP55362K
Accurate characterization of single track-etched, conical nanopores
Patricio Ramirez, Irina V. Blonskaya, Oleg L. Orelovitch, Bozena A. Sartowska
DOI: 10.1039/C4CP01686F
Gap openings in graphene regarding interfacial interaction from substrates
Y. F. Zhu, Q. Q. Dai, W. T. Zheng, Q. Jiang
DOI: 10.1039/C3CP55222E
Trapping of single nano-objects in dynamic temperature fields
Alois Würger
DOI: 10.1039/C4CP01560F
NO oxidation catalysis on copper doped hexagonal phase LaCoO3: a combined experimental and theoretical study
Chen Zhou, Chunzheng Wu, Yanwei Wen, Yejian Xue, Rong Chen, Zhaoliang Zhang, Bin Shan, Hongfeng Yin, Wei Guo Wang
DOI: 10.1039/C3CP54963A
DFT calculations on kinetic data for some [4+2] reactions in solution
Yue Li, De-Cai Fang
DOI: 10.1039/C4CP02068E
Novel high-efficiency crystalline-silicon-based compound heterojunction solar cells: HCT (heterojunction with compound thin-layer)
Yun Sun, Wei Liu, Jianghong Yao
DOI: 10.1039/C4CP00668B
A spectroscopic investigation and molecular docking study on the interaction of hen egg white lysozyme with liposomes of saturated and unsaturated phosphocholines probed by an anticancer drug ellipticine
Anupam Das, Raina Thakur, Anuradha Dagar, Anjan Chakraborty
DOI: 10.1039/C3CP54247E
On the thermodynamics of carbon nanotube single-file water loading: free energy, energy and entropy calculations
Chris Oostenbrink
DOI: 10.1039/C3CP54554G
Fatty acid droplet self-division driven by a chemical reaction
I. Derényi, I. Lagzi
DOI: 10.1039/C3CP54676D
You might also like
What are the main uses of 1-(3-Aminophenyl)-3-[(3R)-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-(2-pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]urea (CAS: 155412-88-7)?
This compound is mainly used as an intermediate in the synthesis of antipsychoti...
How should waste containing 1-(D-Ribofuranosyl)-1,4-dihydro-3-pyridinecarboxamide (CAS: 19132-12-8) be handled?
Waste containing 1-(D-Ribofuranosyl)-1,4-dihydro-3-pyridinecarboxamide (CAS: 191...
What regulatory guidelines apply to 2-Methyl-2-propanyl 3-bromo-3-(hydroxymethyl)-1-azetidinecarboxylate (CAS: 2007919-81-3)?
2-Methyl-2-propanyl 3-bromo-3-(hydroxymethyl)-1-azetidinecarboxylate (CAS: 20079...
What is N-(4-Chloro-2-pyridinyl)acetamide (CAS: 245056-66-0)?
N-(4-Chloro-2-pyridinyl)acetamide (CAS: 245056-66-0) is a chemical compound with...
What is 5-Chloro-2-hydroxybenzoic acid (CAS: 321-14-2)?
5-Chloro-2-hydroxybenzoic acid, also known as 5-chlorosalicylic acid, is an arom...
What precautions should be taken when handling 1,1-Dichloro-1-fluoroethane (CAS: 1717-00-6)?
When handling 1,1-Dichloro-1-fluoroethane (CAS: 1717-00-6), it is important to u...
What are the physical and chemical properties of Fmoc-(2S,3R)-3-phenylpyrrolidine-2-carboxylic acid (CAS: 281655-32-1)?
Fmoc-(2S,3R)-3-phenylpyrrolidine-2-carboxylic acid is a white crystalline solid ...
What are the main uses of 4-Amino-5-bromo-2-pyridinecarboxylic acid (CAS: 1363381-01-4)?
4-Amino-5-bromo-2-pyridinecarboxylic acid is primarily used as a precursor in th...
What precautions should be taken when handling (S)-tert-butyl 2-((2-(4-bromophenyl)-2-oxoethyl)carbamoyl)pyrrolidine-1-carboxylate (CAS: 1007881-98-2)?
Handling this compound should be done with personal protective equipment (PPE) i...
What precautions should be taken when handling 8-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS: 688363-73-7)?
When handling 8-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one, use prop...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.










![Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride structure Methyl 8-azabicyclo[3.2.1]octane-3-carboxylate hydrochloride structure](https://static.chemtradehub.com/structs/179/179022-43-6-77f5.webp)

![2,2'-[(Abieta-8,11,13-trien-18-ylimino)bis(2,1-ethanediyloxy)]diethanol structure 2,2'-[(Abieta-8,11,13-trien-18-ylimino)bis(2,1-ethanediyloxy)]diethanol structure](https://static.chemtradehub.com/structs/513/51344-62-8-8518.webp)

