Understanding the relationship between viral infections and trace elements from a metallomics perspective: implications for COVID-19

文献情報

出版日 2020-11-14
DOI 10.1039/D0MT00220H
インパクトファクター 0
著者

Jemmyson Romário de Jesus, Tatianny de Araújo Andrade



要旨

Recently, the World Health Organization (WHO) declared a pandemic situation due to a new viral infection (COVID-19) caused by a novel virus (Sars-CoV-2). COVID-19 is today the leading cause of death from viral infections in the world. It is known that many elements play important roles in viral infections, both in virus survival, and in the activation of the host's immune system, which depends on the presence of micronutrients to maintain the integrity of its functions. In this sense, the metallome can be an important object of study for understanding viral infections. Therefore, this work presents an overview of the role of trace elements in the immune system and the state of the art in metallomics, highlighting the challenges found in studies focusing on viral infections.

掲載誌

Metallomics

Metallomics
CiteScore: 7
自己引用率: 6.9%
年間論文数: 77

Metallomics publishes cutting-edge investigations aimed at elucidating the identification, distribution, dynamics, role and impact of metals and metalloids in biological systems. Studies that address the “what, where, when, how and why” of these inorganic elements in cells, tissues, organisms, and various environmental niches are welcome, especially those employing multidisciplinary approaches drawn from the analytical, bioinorganic, medicinal, environmental, biophysical, cell biology, plant biology and chemical biology communities. We are particularly interested in articles that enhance our chemical and/or physical understanding of the molecular mechanisms of metal-dependent life processes, and those that probe the common space between metallomics and other ‘omics approaches to uncover new insights into biological processes. Metallomics seeks to position itself at the forefront of those advances in analytical chemistry destined to clarify the enormous complexity of biological systems. As such, we particularly welcome those papers that outline cutting-edge analytical technologies, e.g., in the development and application of powerful new imaging, spectroscopic and mass spectrometric modalities. Work that describes new insights into metal speciation, trafficking and dynamics in complex systems or as a function of microenvironment are also strongly encouraged. Studies that examine the interconnectivity of metal-dependent processes with systems level responses relevant to organismal health or disease are also strongly encouraged, for example those that probe the effect of chemical exposure on metal homeostasis or the impact of metal-based drugs on cellular processes.

おすすめサプライヤー

ドイツSohena GmbH
中国杭州安凯バイオمياهектив製薬有限公司
ドイツLudwig Melosch Vertriebs-GmbH & Co.
ドイツQUANCOM Informationssysteme GmbH
中国襄樊ノール化学有限公司
オーストリアBIOLAB GmbH
中国デジ某种程度天グループ
ドイツOTTO KLEIN GMBH
中国深圳方寸达科技有限公司
中国تعيين지드 verztek科技株式会社
免責事項
このページに表示される学術雑誌情報は、参考および研究目的のみを目的としています。当社は雑誌出版社とは提携しておらず、投稿の取り扱いも行っておりません。出版に関するお問い合わせは、各雑誌出版社に直接ご連絡ください。
表示されている情報に誤りがある場合は、[email protected] までご連絡ください。迅速に確認し、対応いたします。