Generation of a chemical gradient across an array of 256 cell cultures in a single chip
文献情報
Himali Somaweera, Akif Ibragimov
A microfluidic diffusion diluter to create stable chemical gradients across an array of cell cultures was demonstrated. The device enabled concentration based studies to be conducted at 256 different concentrations across individual, low shear cell cultures. A gradient of staurosporine on cells stained with Mitotracker Deep Red (MTDR) showed a concentration-based effect on cell apoptosis across the cell culture array.
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Chemistry of Heterocyclic Compounds
Journal of the American Chemical Society
Journal of the Chinese Chemical Society
Chemistry of Natural Compounds
Australian Journal of Chemistry
Accounts of Chemical Research
Biopolymers
Canadian Metallurgical Quarterly
Advances in Colloid and Interface Science
Chemical & Pharmaceutical Bulletin
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